The ECG provides critical information that assists in establishing the diagnosis of acute coronary syndrome and determining the treatment strategy. In acute coronary syndrome, common ECG abnormalities include T-wave tenting or inversion, ST-segment elevation or depression (including J-point elevation in multiple leads), and pathologic Q waves. ECG risk stratification allows appropriate referral of patients to a chest pain center or, even, to a catheterization laboratory. Thus, in this podcast Dr. Cosentino aims at improving your confidence in the interpretation of ECG during a suspected or confirmed acute coronary syndrome. A systematic approach to ECG analysis is essential for identifying an early and appropriate management for patients with acute coronary syndrome. This podcast is ideal for those required to interpret ECGs during suspected or confirmed acute coronary syndrome within their clinical role and who wish to quickly develop a reliable method for ECG interpretation in this clinical setting.